Tag: tumor cells

Extracellular Matrix and Tumor-Immune Interactions: Challenges & Opportunities

November 12, 2024

“This review explores our current understanding of how ECM geometry influences the behaviors of both immune cells and tumor cells, which in turn impacts treatment efficacy and cancer evolutionary progression.”… read more

Oncotarget

Next-Gen Cell-Penetrating Antibodies for Tumor Targeting and RAD51 Inhibition

October 21, 2024

“Overall, the data presented in this study affirm that humanizing 3E10 preserves its crucial biological properties essential for therapeutic efficacy.” BUFFALO, NY- October 21, 2024 – A new research paper… read more

Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival

Oncotarget

TCR CDR3s and Renalase-1 Linked to Increased Melanoma Survival

August 8, 2024

“These findings indicate that renalase-1 is a potential antigen for TCR recognition in melanoma and could be considered as a target for immunotherapy.” BUFFALO, NY- August 8, 2024 – A… read more

Figure 1: Glutamine metabolism effect in tumor microenvironment cells.

Oncotarget

Inhibiting Glutamine Metabolism Impacts Tumor Cells or the Microenvironment?

August 16, 2023

“These new findings evidence the necessity of more research in Gln metabolism to define the best therapeutic strategies for cancer patients.” BUFFALO, NY- August 16, 2023 – A new editorial… read more

Oncotarget

Behind the Study: Molecular Dialogue Between Tumor Cells and Fibroblasts

May 25, 2023

Dr. Gopal C. Kundu from KIIT Deemed to be University in Odisha, India, describes a recent editorial he co-authored that was published by Oncotarget in Volume 14, entitled, “The molecular… read more

Oncotarget

Behind the Study: Role of Cancer Associated Fibroblasts in Prostate Cancer

March 17, 2022

Dr. Nerymar Ortiz-Otero from the Meinig School of Biomedical Engineering, Cornell University, discusses a research paper she co-authored that was published by Oncotarget in Volume 11, Issue 12, entitled, “Cancer… read more

Oncotarget

Behind the Study: Oral Squamous Carcinoma Cell Migration and Viability

August 30, 2021

Behind the Study is a series of transcribed videos from researchers elaborating on their oncology-focused studies published by Oncotarget. A new Behind the Study is released each Monday. Visit the Oncotarget YouTube channel for more… read more